[Fis] FIS: DNA and bioinformatics

Dear colleagues,
     1) Thank you very much to Shu Kun for his interesting papers. I�ll try
to understand it deeply and to apply it in my researches. If I have a
success in this way, I�ll be glad to inform Shu Kun and all of you.
     2) Concerning to the theme of information from genetic molecules,
proposed by Pedro for our dicussion, I would like to say the following. It�s
well known, that kinds of biological organisms are very different from each
other from many viewpoints. For example, they have different morphology of
their bodies, different types of locomotion (some of organisms can walk,
others can swim, others can fly, others can creep, etc), different types of
reproduction systems, etc. Against this background of differences among
organisms, molecular genetics has discovered in the past century a striking
fact that just from the information-hereditary viewpoint all biological
organisms are unified wonderfully: all of them have identical bases of
system of genetic coding - from bacteria up to a whale and from worm up to a
bird and man. In other words, a great union of biological organisms has been
happened in science. From this moment the information viewpoint on
biological objects became more and more fundamental and interesting for many
scientists year by year.
>From the information viewpoint, biological organisms are information
essences. They live due to receiving of the genetic information from the
ancestors, and they exist to transfer the genetic information to their
descendants. All physical, chemical, cybernetic and others mechanisms can be
considered in the frame of this viewpoint as secondary supporting equipments
to provide this main biological task of stable bio-information flow. In the
biological literature it is possible quite often to meet the statement now
that biological organisms are the texts since a molecular level of their
organization.
It�s very probable that no one from physiological systems can survive in
biological evolution without structural agreement with structure of genetic
code because of a simple reason that such physiological system can�t be
transmitted to descendants. Darwin�s theory of natural selection has paid a
main attention to importance of factors of external surroundings for natural
selection of organisms. In my opinion, facts of molecular
genetic-information union of biological organisms put forward a new problem
of natural selection: a problem of natural selection of physiological
systems according to internal (for each kind of organisms) factors of their
structural agreement with basic structure of genetic coding. One can suppose
that all physiological systems and processes, including of world perception
and of theoretical and cultural activities of people, have such stamp of
their agreement with basic genetic structures. This is a reason of special
importance of a problem of information genetic molecules for science in a
whole.
     In my own researches of genetic code I have discovered that so named
�elementary� alphabet of genetic code isn�t elementary but consists of three
binary sub-alphabets due to objective biochemical attributes of its
elements. This circumstances lead to many essential consequences. My first
publication in English on these results is presented at FIS site
http://fis.iguw.tuwien.ac.at/recources/papers.html in my article �Genetic
Code and the Ancient Chinese �Book of Changes��. This publication is based
at my book: S.V.Petoukhov �Biperiodic Table of Genetic Code and Number of
Protons�, Moscow, 2001, 258 p. (in Russian; information on this book, on its
content, etc. in English is at site
http://members.tripod.com/vismath/sg/petoukhov.htm ). I prolong these
researches now intensively. A few of them is presenting in these days in my
report �The Biperiodic Table and Attributive Conception of Genetic Code. A
Problem of Unification Bases of Biological Languages� at �The 2003
International Conference on Mathematics and Engineering Techniques in
Medicine and Biological Sciences� (session �Bioinformatics 2003�, June
23-26, 2003, Las Vegas, Nevada, USA). The paper should be published in the
Proceedings and CD-ROMs of the Conference.
My results have permitted to introduce binary numbers and binary sequences
in bioinformatics in analogical manner with binary sequences of computer
informatics. Thank you very much to Jerry for his last information for
FISers about the Symposium "Digital Biology: The Emerging Paradigm"
(November 6-7, 2003). This title is very close to my results in genetic
coding and to my modern attempts to understand biological organisms. New
paradigm of digital biology seems to be very perspective. Of course, it
doesn�t close many other ways to investigate biological organisms from
alternative initial viewpoints.
Thank you very much to all FIZers who participate in our Internet�s
scientific discussions. Specially thanks to organizers of these discussions.
As to me, I read all FIZErs letters attentively and get valuable information
and inspiration from them. Unfortunately I have no possibility to
participate in all FIS-actions as active as I want.

        Best regards,
        Sergei

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Received on Mon Jun 23 12:31:12 2003