Re: [Fis] Molecular recognition: Similarity rule and complementarity rule

From: <jlrchand@erols.com>
Date: Fri 11 Jul 2003 - 17:53:48 CEST

Pedro:

I am uncertain what you mean by taxonomy.

Is this a listing in the sense of Karl?

Or a grouping in the sense of Michael?

In other words, what is the source of the taxonomic structure?

Cheers

Jerry

>Thanks, Shu-Kun, for the well posed questions.
>
>In a paper, posted at the fis site, I have put together a brute
>taxonomy of biomolecular recognition events (inspired in Meggs,
>1998):
>
>enzymes/substrates,
>enzymes/effectors,
>enzymes/cofactors
>antibodies/antigens,
>receptors/transmitters,
>receptors/hormones,
>channels/ions,
>channels/ligands
>nucleotides/DNA-RNA chains,
>RNA/RNA pairing,
>RNA/DNA pairing,
>DNA/DNA pairing,
>DNA/promoters,
>DNA/histones,
>RNA/ribosomes,
>amino acids/protein chains,
>proteins/chaperons,
>proteins/proteasomes,
>proteins/protein multimers,
>proteins/protein complexes,
>proteins/protein kinases-phosphatases,
>tubulins/microtubules,
>actins/microfilaments
>carbohidrates/glycoproteins,
>lipids/lipoproteins,
> phospholipids/membranes
>
>
>>There seem to be only similarity rule and complementarity rule
>>for molecular recognition. Are there any other rules?
>>
Received on Fri Jul 11 17:44:15 2003

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